The Phospho-Histone H3 (S10) Antibody from MyBioSource.com is a Mouse Monoclonal antibody to H3-3A, H3-3B, H3.3 histone A, and H3.3 histone B. This antibody recognizes Human, Mouse, Rat, C. elegans/Worm, Chicken/Bird, Drosophila/Arthropod, Porcine, Rabbit, Xenopus/Amphibian, Yeast/Fungi, and Zebrafish/Fish antigen. The Phospho-Histone H3 (S10) Antibody has been validated for the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded is a replication-independent member of the histone H3 family